Omphalocele is a
central defect of umbilical ring, resulting in persistent herniation of the
abdominal content. The midgut, positioned in umbilical cord, rotates 90°counterclockwise around the superior mesenteric artery.
At 10 weeks of
gestation, intestines return to the abdomen. The small intestines return first,
followed by large intestines, which complete an additional 180°
counterclockwise rotation. After the intestines return to the abdomen, they
enlarge, lengthen, and fuse to the abdominal cavity. The abdominal wall then
closes and the body stalk constricts to become umbilical cord. Omphalocele
results due to either the developmental arrest of the abdominal wall or failure
of the abdominal viscera to return to the abdominal cavity. Read more>>>>>>>>>>>>>>

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